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Search Results for " gsk3 inhibitor 1 "

9

Compounds

Cat No. Product Name Synonyms Targets
T9987 GSK3-IN-1 GSK-3
GSK3-IN-1 is a GSK3B-glycogen synthase kinase-3 beta inhibitor.
T11468 GSK-3 inhibitor 1 GSK-3
GSK-3 inhibitor 1 is a GSK-3 inhibitor.
T73270 GSK3-IN-2 GSK-3
GSK3-IN-2 is a potent GSK3 inhibitor for the treatment of diabetes and neurodegenerative diseases.
T64366 GSK3-IN-4 GSK-3
GSK3-IN-4 is a GSK-3 inhibitor with IC50 of 0.101-1 μM of GSK-3α and GSK-3β in Calipe Assay.
T8969 API-1 NSC177223 Akt
API-1 (NSC-177223) is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .
T36689 KuWal151
Potent and selective CLK inhibitor (IC50 values are 28, 88 and 510 nM for CLK4, 1 and 2, respectively). Exhibits no significant activity at CLK3, DYRK, CDK or GSK3 at a concentration of 10 μM. Inhibits growth of a range ...
T79562 Leucettinib-92 CDK
Leucettinib-92 (compound 92) is a kinase inhibitor selective for DYRK/CLK families, displaying IC50 values of 147 nM (CLK1), 39 nM (CLK2), 5.2 nM (CLK4), 0.8 μM (CLK3), 124 nM (DYRK1A), 204 nM (DYRK1B), 0.16 μM (DYRK2), ...
T35560 SAR502250
SAR502250 is a potent, selective, ATP-competitive, orally active, and brain-penetrant GSK3 inhibitor with a human GSK-3β IC50 value of 12 nM. It exhibits antidepressant-like activity and is being researched for potential...
T79254 Antitrypanosomal agent 14 Parasite
Antitrypanosomal agent 14 (Compound 1), a potent T. brucei inhibitor with an effective concentration (EC50) of 0.47 μM, also inhibits Tb GSK3 with an inhibitory concentration (IC50) of 12 μM, and is utilized in the resea...
TargetMol